《英文msh词典》DNA,Heteroduplex
[入口词] DNA,Heteroduplex
[主题词] Nucleic Acid Heteroduplexes
[英文释义] Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo,these heteroduplexes can result from mutation or genetic recombination; in vitro,they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids.