An [endogenous] [cannabinoid] neurotransmitter. Translation: The natural form of [THC] made in the body that can get you high without weed.
> Tom: Yo what's wrong with you?
> Jerry: Dude I got so high off of anandamide yesterday... WTF ARE YOU DOING WITH THAT FLAMETHROWER!!!
> Tom: Relax, its just a sandwich man