《英文msh词典》Hereditary Multiple Exostoses
[同义词] Hereditary Multiple Exostoses
[主题词] Exostoses,Multiple Hereditary
[中文释义] 遗传性多发性外生骨疣
[英文释义] Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign,bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.