《英文msh词典》Histone H1 Kinase,M-Phase-Specific
[同义词] Histone H1 Kinase,M-Phase-Specific
[主题词] Maturation-Promoting Factor
[中文释义] 组蛋白H1激酶,M期特异性
[英文释义] Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown,chromosome condensation,spindle assembly,and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.