《英文msh词典》Histone H1 Kinase,M Phase Specific
[入口词] Histone H1 Kinase,M Phase Specific
[主题词] Maturation-Promoting Factor
[英文释义] Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown,chromosome condensation,spindle assembly,and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.