《英文msh词典》Holocarboxylase Synthetase Deficiencies
[入口词] Holocarboxylase Synthetase Deficiencies
[主题词] Holocarboxylase Synthetase Deficiency
[英文释义] The neonatal form of MULTIPLE CARBOXYLASE DEFICIENCY that is caused by a defect or deficiency in holocarboxylase synthetase. HLCS is the enzyme that covalently links biotin to the biotin dependent carboxylases (propionyl-CoA-carboxylase,pyruvate carboxylase,and beta-methylcrotonyl-CoA carboxylase).