《英文msh词典》Idiotype,Immunoglobulin
[入口词] Idiotype,Immunoglobulin
[主题词] Immunoglobulin Idiotypes
[英文释义] Unique,genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g.,another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.