《英文msh词典》Kininogens,High-Molecular-Weight
[入口词] Kininogens,High-Molecular-Weight
[主题词] Kininogen,High-Molecular-Weight
[英文释义] A plasma protein,molecular weight of 110 kD,that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction,XIIa,in turn activates prekallikrein to KALLIKREINS. (From Stedman,26th ed)