《英文msh词典》Methylenetetrahydrofolate Dehydrogenase (NADP)
[主题词] Methylenetetrahydrofolate Dehydrogenase (NADP)
[同义词] Methylenetetrahydrofolate Dehydrogenase (NADP+)
[入口词] Methylenetetrahydrofolate Dehydrogenase
[入口词] Dehydrogenase,Methylenetetrahydrofolate
[英文释义] An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher eukaryotes a trifunctional enzyme exists with additional METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE and FORMATE-TETRAHYDROFOLATE LIGASE activity. The enzyme plays an important role in the synthesis of 5-methyltetrahydrofolate,the methyl donor for the VITAMIN B12-dependent remethylation of HOMOCYSTEINE to METHIONINE via METHIONINE SYTHASE.