《英文msh词典》Phosphofructo-1-kinase Isozyme A
[入口词] Phosphofructo-1-kinase Isozyme A
[主题词] Phosphofructokinase-1,Muscle Type
[英文释义] An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans,PHOSPHOFRUCTOSKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII,also known as Tarui's disease.