| 释义 |
Receptor,neu
《英文msh词典》Receptor,neu [同义词] Receptor,neu [主题词] Receptor,erbB-2 [中文释义] 受体,neu [英文释义] A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR,EPIDERMAL GROWTH FACTOR),the erbB-3 receptor (RECEPTOR,ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. |