《英文msh词典》Retinoblastoma Genes
[同义词] Retinoblastoma Genes
[主题词] Genes,Retinoblastoma
[中文释义] 成视网膜细胞瘤基因
[英文释义] Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.