《英文msh词典》5 Aminolevulinate Synthetase
[入口词] 5 Aminolevulinate Synthetase
[主题词] 5-Aminolevulinate Synthetase
[英文释义] An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyl phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis and,in liver at least,is feedback inhibited by heme. (Dorland,28th ed) EC 2.3.1.37.