| 单词 | Cytochrome P 450 CYP11B1 |
| 释义 | Cytochrome P 450 CYP11B1《英文msh词典》Cytochrome P 450 CYP11B1 [入口词] Cytochrome P 450 CYP11B1 [主题词] Steroid 11-beta-Hydroxylase [英文释义] A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP11B1 gene,is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA,CONGENITAL). |
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